MONDAY, Sept. 19 (HealthDay News) — Prescription drugs are about 24 percent cheaper when bought on Canadian Internet sites than when purchased from the online sites of major U.S. pharmacy chains, new research finds.

The price difference would be even higher if prices at Canadian internet sites were compared to walk-in U.S. pharmacies, said Dr. Mark Eisenberg, senior author of the study, appearing in the Sept. 20 issue of the Annals of Internal Medicine.

“There’s a huge, huge outlay for pharmaceuticals in the U.S, and prices are artificially high,” said Eisenberg, an associate professor of medicine at McGill University in Montreal. “The same exact drug manufactured by the same exact company costs much less in Canada, so people in the U.S. are paying higher prices than they have to.”

The findings were hailed by some activists in the field.

“On a drug-by-drug basis, someone could save well over $1,000 a year. For someone who is not covered by the soon-to-be-rolled out Medicare program and isn’t elderly and doesn’t have any coverage, $1,000 is huge,” said Sharon Treat, executive director of the National Legislative Association on Prescription Drug Prices in Hallowell, Maine. “It explains why some people are doing this. It explains why at least 22 states this year looked at legislation addressing importation.” The association acts as a clearinghouse for information for legislators interested in this issue.

“While there is a widespread perception that prescription drugs are less expensive in Canada, there has not been much research to back this up. Everybody says it’s cheaper in Canada and no one knows if it is and, if so, by how much,” Eisenberg said.

In the United States, soaring prescription drug costs and the growth of the Internet have fueled cross-border drug sales in recent years, with one U.S. Department of Heath and Human Services study estimating that more than 12 million prescriptions destined for American patients were filled by Canadian pharmacies in 2003 alone, for a total $700 million in sales.

The U.S. Government Accountability Office recently reported a 25 percent overall increase in U.S. retail drug prices from 2000 to 2004. Price hikes for two brand-name drugs from Pfizer Inc., Lipitor and Celebrex, had the most impact on that increase.

While the Bush administration has firmly opposed legalizing drug imports, government leaders in various U.S. states and cities have set up programs to help cash-strapped residents buy their pharmaceuticals from Canada.

The U.S. Congress is expected to pass legislation to ease Internet drug sales. But in a new twist, the Ottawa government, concerned that pharmacy sales to the U.S. may cause domestic shortages in Canada, is drafting legislation to restrict bulk exports of Canadian drugs, although the legislation is not likely to be as severe as once feared. Any changes would probably not happen till later this year.

The authors of this study compared prices on 44 common brand-name medications at 12 highly ranked Canadian internet pharmacies and three major online U.S. chain pharmacies: CVS, Rite Aid and Walgreen’s.

The survey, conducted at the end of 2004, found that 41 of 44 medications were less expensive on Internet sites north of the border.

The medications with the largest mean yearly savings were Zyprexa (for schizophrenia and bipolar disorder) with annual savings of $1,159, Actos (for control of diabetes), with savings of $852, and Nexium (for heartburn), with savings of $772.

Only three medications, all of them for erectile dysfunction, were more expensive in Canada. This is because so-called lifestyle drugs do not have the same price controls as drugs that are considered “vital,” Eisenberg explained.

The seo tips mean savings at Canadian internet pharmacies was 24 percent per dose.

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